GrippeCanadaV4, Main, Exploration, bibRecord, 000049

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.

Identifieur interne : 000049 ( Main/Exploration ); précédent : 000048; suivant : 000050

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.

Auteurs : Carita Ng [Canada] ; Lingyun Ye [Canada] ; Stephen G. Noorduyn [Canada] ; Margaret Hux [Canada] ; Edward Thommes [Canada] ; Ron Goeree [Canada] ; Ardith Ambrose [Canada] ; Melissa K. Andrew [Canada] ; Todd Hatchette [Canada] ; Guy Boivin [Canada] ; William Bowie [Canada] ; May Elsherif [Canada] ; Karen Green [Canada] ; Jennie Johnstone [Canada] ; Kevin Katz [Canada] ; Jason Leblanc [Canada] ; Mark Loeb [Canada] ; Donna Mackinnon-Cameron [Canada] ; Anne Mccarthy [Canada] ; Janet Mcelhaney [Canada] ; Allison Mcgeer [Canada] ; Andre Poirier [Canada] ; Jeff Powis [Canada] ; David Richardson [Canada] ; Rohita Sharma [Canada] ; Makeda Semret [Canada] ; Stephanie Smith [Canada] ; Daniel Smyth [Canada] ; Grant Stiver [Canada] ; Sylvie Trottier [Canada] ; Louis Valiquette [Canada] ; Duncan Webster [Canada] ; Shelly A. Mcneil [Canada]

Source :

Influenza and other respiratory viruses [ 1750-2659 ] ; 2018.

RBID : pubmed:29125689

Descripteurs français

KwdFr :
- Adolescent (MeSH), Adulte (MeSH), Adulte d'âge moyen (MeSH), Canada (épidémiologie), Coûts des soins de santé (MeSH), Femelle (MeSH), Grippe humaine (anatomopathologie), Grippe humaine (économie), Grippe humaine (épidémiologie), Hospitalisation (MeSH), Humains (MeSH), Jeune adulte (MeSH), Mâle (MeSH), Ressources en santé (MeSH), Sujet âgé (MeSH), Sujet âgé de 80 ans ou plus (MeSH).
MESH :
- anatomopathologie : Grippe humaine.
- économie : Grippe humaine.
- épidémiologie : Canada, Grippe humaine.
- Adolescent, Adulte, Adulte d'âge moyen, Coûts des soins de santé, Femelle, Hospitalisation, Humains, Jeune adulte, Mâle, Ressources en santé, Sujet âgé, Sujet âgé de 80 ans ou plus.
Wicri :
- geographic : Canada.

English descriptors

KwdEn :
- Adolescent (MeSH), Adult (MeSH), Aged (MeSH), Aged, 80 and over (MeSH), Canada (epidemiology), Female (MeSH), Health Care Costs (MeSH), Health Resources (MeSH), Hospitalization (MeSH), Humans (MeSH), Influenza, Human (economics), Influenza, Human (epidemiology), Influenza, Human (pathology), Male (MeSH), Middle Aged (MeSH), Young Adult (MeSH).
MESH :
- geographic , epidemiology : Canada.
- economics : Influenza, Human.
- epidemiology : Influenza, Human.
- pathology : Influenza, Human.
- Adolescent, Adult, Aged, Aged, 80 and over, Female, Health Care Costs, Health Resources, Hospitalization, Humans, Male, Middle Aged, Young Adult.

Abstract

BACKGROUND

Consideration of cost determinants is crucial to inform delivery of public vaccination programs.

OBJECTIVES

To estimate the average total cost of laboratory-confirmed influenza requiring hospitalization in Canadians prior to, during, and 30 days following discharge. To analyze effects of patient/disease characteristics, treatment, and regional differences in costs.

METHODS

Study utilized previously recorded clinical characteristics, resource use, and outcomes of laboratory-confirmed influenza patients admitted to hospitals in the Serious Outcomes Surveillance (SOS), Canadian Immunization Research Network (CIRN), from 2010/11 to 2012/13. Unit costs including hospital overheads were linked to inpatient/outpatient resource utilization before and after admissions.

RESULTS

Dataset included 2943 adult admissions to 17 SOS Network hospitals and 24 Toronto Invasive Bacterial Disease Network hospitals. Mean age was 69.5 years. Average hospital stay was 10.8 days (95% CI: 10.3, 11.3), general ward stays were 9.4 days (95% CI: 9.0, 9.8), and ICU stays were 9.8 days (95% CI: 8.6, 11.1) for the 14% of patients admitted to the ICU. Average cost per case was $14 612 CAD (95% CI: $13 852, $15 372) including $133 (95% CI: $116, $150) for medical care prior to admission, $14 031 (95% CI: $13 295, $14 768) during initial hospital stay, $447 (95% CI: $271, $624) post-discharge, including readmission within 30 days.

CONCLUSION

The cost of laboratory-confirmed influenza was higher than previous estimates, driven mostly by length of stay and analyzing only laboratory-confirmed influenza cases. The true per-patient cost of influenza-related hospitalization has been underestimated, and prevention programs should be evaluated in this context.

DOI: 10.1111/irv.12521
PubMed: 29125689
PubMed Central: PMC5820421

Affiliations:

Links toward previous steps (curation, corpus...)

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Le document en format XML

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<author><name sortKey="Loeb, Mark" sort="Loeb, Mark" uniqKey="Loeb M" first="Mark" last="Loeb">Mark Loeb</name>
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<author><name sortKey="Mackinnon Cameron, Donna" sort="Mackinnon Cameron, Donna" uniqKey="Mackinnon Cameron D" first="Donna" last="Mackinnon-Cameron">Donna Mackinnon-Cameron</name>
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<author><name sortKey="Powis, Jeff" sort="Powis, Jeff" uniqKey="Powis J" first="Jeff" last="Powis">Jeff Powis</name>
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<author><name sortKey="Richardson, David" sort="Richardson, David" uniqKey="Richardson D" first="David" last="Richardson">David Richardson</name>
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<author><name sortKey="Sharma, Rohita" sort="Sharma, Rohita" uniqKey="Sharma R" first="Rohita" last="Sharma">Rohita Sharma</name>
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<author><name sortKey="Semret, Makeda" sort="Semret, Makeda" uniqKey="Semret M" first="Makeda" last="Semret">Makeda Semret</name>
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<author><name sortKey="Smith, Stephanie" sort="Smith, Stephanie" uniqKey="Smith S" first="Stephanie" last="Smith">Stephanie Smith</name>
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<author><name sortKey="Stiver, Grant" sort="Stiver, Grant" uniqKey="Stiver G" first="Grant" last="Stiver">Grant Stiver</name>
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<country xml:lang="fr">Canada</country>
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<author><name sortKey="Trottier, Sylvie" sort="Trottier, Sylvie" uniqKey="Trottier S" first="Sylvie" last="Trottier">Sylvie Trottier</name>
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<country xml:lang="fr">Canada</country>
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<author><name sortKey="Valiquette, Louis" sort="Valiquette, Louis" uniqKey="Valiquette L" first="Louis" last="Valiquette">Louis Valiquette</name>
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<author><name sortKey="Webster, Duncan" sort="Webster, Duncan" uniqKey="Webster D" first="Duncan" last="Webster">Duncan Webster</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>Horizon Health, Saint John, NB</wicri:regionArea>
<wicri:noRegion>NB</wicri:noRegion>
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<author><name sortKey="Mcneil, Shelly A" sort="Mcneil, Shelly A" uniqKey="Mcneil S" first="Shelly A" last="Mcneil">Shelly A. Mcneil</name>
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<sourceDesc><biblStruct><analytic><title xml:lang="en">Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.</title>
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<author><name sortKey="Noorduyn, Stephen G" sort="Noorduyn, Stephen G" uniqKey="Noorduyn S" first="Stephen G" last="Noorduyn">Stephen G. Noorduyn</name>
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<author><name sortKey="Hux, Margaret" sort="Hux, Margaret" uniqKey="Hux M" first="Margaret" last="Hux">Margaret Hux</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>ICON Plc, Vancouver, BC</wicri:regionArea>
<wicri:noRegion>BC</wicri:noRegion>
</affiliation>
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<author><name sortKey="Thommes, Edward" sort="Thommes, Edward" uniqKey="Thommes E" first="Edward" last="Thommes">Edward Thommes</name>
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<country xml:lang="fr">Canada</country>
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<wicri:noRegion>ON</wicri:noRegion>
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<author><name sortKey="Goeree, Ron" sort="Goeree, Ron" uniqKey="Goeree R" first="Ron" last="Goeree">Ron Goeree</name>
<affiliation wicri:level="4"><nlm:affiliation>McMaster University, Hamilton, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>McMaster University, Hamilton, ON</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Ambrose, Ardith" sort="Ambrose, Ardith" uniqKey="Ambrose A" first="Ardith" last="Ambrose">Ardith Ambrose</name>
<affiliation wicri:level="1"><nlm:affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
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</author>
<author><name sortKey="Andrew, Melissa K" sort="Andrew, Melissa K" uniqKey="Andrew M" first="Melissa K" last="Andrew">Melissa K. Andrew</name>
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<country xml:lang="fr">Canada</country>
<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
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</author>
<author><name sortKey="Hatchette, Todd" sort="Hatchette, Todd" uniqKey="Hatchette T" first="Todd" last="Hatchette">Todd Hatchette</name>
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<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
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</author>
<author><name sortKey="Boivin, Guy" sort="Boivin, Guy" uniqKey="Boivin G" first="Guy" last="Boivin">Guy Boivin</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre Hospitalier Universitaire de Québec, Québec, QC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Centre Hospitalier Universitaire de Québec, Québec, QC</wicri:regionArea>
<wicri:noRegion>QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Bowie, William" sort="Bowie, William" uniqKey="Bowie W" first="William" last="Bowie">William Bowie</name>
<affiliation wicri:level="1"><nlm:affiliation>University of British Columbia, Vancouver, BC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>University of British Columbia, Vancouver, BC</wicri:regionArea>
<wicri:noRegion>BC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Elsherif, May" sort="Elsherif, May" uniqKey="Elsherif M" first="May" last="Elsherif">May Elsherif</name>
<affiliation wicri:level="1"><nlm:affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Green, Karen" sort="Green, Karen" uniqKey="Green K" first="Karen" last="Green">Karen Green</name>
<affiliation wicri:level="1"><nlm:affiliation>Mount Sinai Hospital, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Mount Sinai Hospital, Toronto, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Johnstone, Jennie" sort="Johnstone, Jennie" uniqKey="Johnstone J" first="Jennie" last="Johnstone">Jennie Johnstone</name>
<affiliation wicri:level="4"><nlm:affiliation>McMaster University, Hamilton, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>McMaster University, Hamilton, ON</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
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</author>
<author><name sortKey="Katz, Kevin" sort="Katz, Kevin" uniqKey="Katz K" first="Kevin" last="Katz">Kevin Katz</name>
<affiliation wicri:level="1"><nlm:affiliation>North York General Hospital, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>North York General Hospital, Toronto, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
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<author><name sortKey="Leblanc, Jason" sort="Leblanc, Jason" uniqKey="Leblanc J" first="Jason" last="Leblanc">Jason Leblanc</name>
<affiliation wicri:level="1"><nlm:affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Loeb, Mark" sort="Loeb, Mark" uniqKey="Loeb M" first="Mark" last="Loeb">Mark Loeb</name>
<affiliation wicri:level="4"><nlm:affiliation>McMaster University, Hamilton, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>McMaster University, Hamilton, ON</wicri:regionArea>
<orgName type="university">Université McMaster</orgName>
<placeName><settlement type="city">Hamilton (Ontario)</settlement>
<region type="state">Ontario</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mackinnon Cameron, Donna" sort="Mackinnon Cameron, Donna" uniqKey="Mackinnon Cameron D" first="Donna" last="Mackinnon-Cameron">Donna Mackinnon-Cameron</name>
<affiliation wicri:level="1"><nlm:affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mccarthy, Anne" sort="Mccarthy, Anne" uniqKey="Mccarthy A" first="Anne" last="Mccarthy">Anne Mccarthy</name>
<affiliation wicri:level="1"><nlm:affiliation>The Ottawa Hospital, Ottawa Hospital Civic Campus, Ottawa, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>The Ottawa Hospital, Ottawa Hospital Civic Campus, Ottawa, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mcelhaney, Janet" sort="Mcelhaney, Janet" uniqKey="Mcelhaney J" first="Janet" last="Mcelhaney">Janet Mcelhaney</name>
<affiliation wicri:level="1"><nlm:affiliation>Health Sciences North Research Institute, Sudbury, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Health Sciences North Research Institute, Sudbury, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mcgeer, Allison" sort="Mcgeer, Allison" uniqKey="Mcgeer A" first="Allison" last="Mcgeer">Allison Mcgeer</name>
<affiliation wicri:level="1"><nlm:affiliation>Mount Sinai Hospital, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Mount Sinai Hospital, Toronto, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Poirier, Andre" sort="Poirier, Andre" uniqKey="Poirier A" first="Andre" last="Poirier">Andre Poirier</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre de santé et de service sociaux de Trois-Rivières, Trois Rivières, QC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Centre de santé et de service sociaux de Trois-Rivières, Trois Rivières, QC</wicri:regionArea>
<wicri:noRegion>QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Powis, Jeff" sort="Powis, Jeff" uniqKey="Powis J" first="Jeff" last="Powis">Jeff Powis</name>
<affiliation wicri:level="1"><nlm:affiliation>Michael Garron Hospital, Toronto, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Michael Garron Hospital, Toronto, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Richardson, David" sort="Richardson, David" uniqKey="Richardson D" first="David" last="Richardson">David Richardson</name>
<affiliation wicri:level="1"><nlm:affiliation>Department of Infectious Diseases and Medical Microbiology, William Osler Health System, Brampton, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Department of Infectious Diseases and Medical Microbiology, William Osler Health System, Brampton, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sharma, Rohita" sort="Sharma, Rohita" uniqKey="Sharma R" first="Rohita" last="Sharma">Rohita Sharma</name>
<affiliation wicri:level="1"><nlm:affiliation>GSK, Mississauga, ON, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>GSK, Mississauga, ON</wicri:regionArea>
<wicri:noRegion>ON</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Semret, Makeda" sort="Semret, Makeda" uniqKey="Semret M" first="Makeda" last="Semret">Makeda Semret</name>
<affiliation wicri:level="1"><nlm:affiliation>McGill University Health Centre, McGill University, Montreal, QC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>McGill University Health Centre, McGill University, Montreal, QC</wicri:regionArea>
<wicri:noRegion>QC</wicri:noRegion>
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</author>
<author><name sortKey="Smith, Stephanie" sort="Smith, Stephanie" uniqKey="Smith S" first="Stephanie" last="Smith">Stephanie Smith</name>
<affiliation wicri:level="1"><nlm:affiliation>University of Alberta Hospital, Edmonton, AB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>University of Alberta Hospital, Edmonton, AB</wicri:regionArea>
<wicri:noRegion>AB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Smyth, Daniel" sort="Smyth, Daniel" uniqKey="Smyth D" first="Daniel" last="Smyth">Daniel Smyth</name>
<affiliation wicri:level="1"><nlm:affiliation>The Moncton Hospital, Moncton, NB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>The Moncton Hospital, Moncton, NB</wicri:regionArea>
<wicri:noRegion>NB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stiver, Grant" sort="Stiver, Grant" uniqKey="Stiver G" first="Grant" last="Stiver">Grant Stiver</name>
<affiliation wicri:level="1"><nlm:affiliation>University of British Columbia, Vancouver, BC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>University of British Columbia, Vancouver, BC</wicri:regionArea>
<wicri:noRegion>BC</wicri:noRegion>
</affiliation>
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<author><name sortKey="Trottier, Sylvie" sort="Trottier, Sylvie" uniqKey="Trottier S" first="Sylvie" last="Trottier">Sylvie Trottier</name>
<affiliation wicri:level="1"><nlm:affiliation>Centre Hospitalier Universitaire de Québec, Québec, QC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Centre Hospitalier Universitaire de Québec, Québec, QC</wicri:regionArea>
<wicri:noRegion>QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Valiquette, Louis" sort="Valiquette, Louis" uniqKey="Valiquette L" first="Louis" last="Valiquette">Louis Valiquette</name>
<affiliation wicri:level="1"><nlm:affiliation>Université de Sherbrooke, Sherbrooke, QC, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Université de Sherbrooke, Sherbrooke, QC</wicri:regionArea>
<wicri:noRegion>QC</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Webster, Duncan" sort="Webster, Duncan" uniqKey="Webster D" first="Duncan" last="Webster">Duncan Webster</name>
<affiliation wicri:level="1"><nlm:affiliation>Horizon Health, Saint John, NB, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Horizon Health, Saint John, NB</wicri:regionArea>
<wicri:noRegion>NB</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Mcneil, Shelly A" sort="Mcneil, Shelly A" uniqKey="Mcneil S" first="Shelly A" last="Mcneil">Shelly A. Mcneil</name>
<affiliation wicri:level="1"><nlm:affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</nlm:affiliation>
<country xml:lang="fr">Canada</country>
<wicri:regionArea>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS</wicri:regionArea>
<wicri:noRegion>NS</wicri:noRegion>
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<series><title level="j">Influenza and other respiratory viruses</title>
<idno type="eISSN">1750-2659</idno>
<imprint><date when="2018" type="published">2018</date>
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<term>Adult (MeSH)</term>
<term>Aged (MeSH)</term>
<term>Aged, 80 and over (MeSH)</term>
<term>Canada (epidemiology)</term>
<term>Female (MeSH)</term>
<term>Health Care Costs (MeSH)</term>
<term>Health Resources (MeSH)</term>
<term>Hospitalization (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Influenza, Human (economics)</term>
<term>Influenza, Human (epidemiology)</term>
<term>Influenza, Human (pathology)</term>
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<term>Canada (épidémiologie)</term>
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<term>Femelle (MeSH)</term>
<term>Grippe humaine (anatomopathologie)</term>
<term>Grippe humaine (économie)</term>
<term>Grippe humaine (épidémiologie)</term>
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<term>Hospitalization</term>
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<term>Adulte</term>
<term>Adulte d'âge moyen</term>
<term>Coûts des soins de santé</term>
<term>Femelle</term>
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<front><div type="abstract" xml:lang="en"><p><b>BACKGROUND</b>
</p>
<p>Consideration of cost determinants is crucial to inform delivery of public vaccination programs.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b>
</p>
<p>To estimate the average total cost of laboratory-confirmed influenza requiring hospitalization in Canadians prior to, during, and 30 days following discharge. To analyze effects of patient/disease characteristics, treatment, and regional differences in costs.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>METHODS</b>
</p>
<p>Study utilized previously recorded clinical characteristics, resource use, and outcomes of laboratory-confirmed influenza patients admitted to hospitals in the Serious Outcomes Surveillance (SOS), Canadian Immunization Research Network (CIRN), from 2010/11 to 2012/13. Unit costs including hospital overheads were linked to inpatient/outpatient resource utilization before and after admissions.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>RESULTS</b>
</p>
<p>Dataset included 2943 adult admissions to 17 SOS Network hospitals and 24 Toronto Invasive Bacterial Disease Network hospitals. Mean age was 69.5 years. Average hospital stay was 10.8 days (95% CI: 10.3, 11.3), general ward stays were 9.4 days (95% CI: 9.0, 9.8), and ICU stays were 9.8 days (95% CI: 8.6, 11.1) for the 14% of patients admitted to the ICU. Average cost per case was $14 612 CAD (95% CI: $13 852, $15 372) including $133 (95% CI: $116, $150) for medical care prior to admission, $14 031 (95% CI: $13 295, $14 768) during initial hospital stay, $447 (95% CI: $271, $624) post-discharge, including readmission within 30 days.</p>
</div>
<div type="abstract" xml:lang="en"><p><b>CONCLUSION</b>
</p>
<p>The cost of laboratory-confirmed influenza was higher than previous estimates, driven mostly by length of stay and analyzing only laboratory-confirmed influenza cases. The true per-patient cost of influenza-related hospitalization has been underestimated, and prevention programs should be evaluated in this context.</p>
</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">29125689</PMID>
<DateCompleted><Year>2019</Year>
<Month>01</Month>
<Day>29</Day>
</DateCompleted>
<DateRevised><Year>2020</Year>
<Month>04</Month>
<Day>20</Day>
</DateRevised>
<Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Electronic">1750-2659</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>12</Volume>
<Issue>2</Issue>
<PubDate><Year>2018</Year>
<Month>03</Month>
</PubDate>
</JournalIssue>
<Title>Influenza and other respiratory viruses</Title>
<ISOAbbreviation>Influenza Other Respir Viruses</ISOAbbreviation>
</Journal>
<ArticleTitle>Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.</ArticleTitle>
<Pagination><MedlinePgn>232-240</MedlinePgn>
</Pagination>
<ELocationID EIdType="doi" ValidYN="Y">10.1111/irv.12521</ELocationID>
<Abstract><AbstractText Label="BACKGROUND">Consideration of cost determinants is crucial to inform delivery of public vaccination programs.</AbstractText>
<AbstractText Label="OBJECTIVES">To estimate the average total cost of laboratory-confirmed influenza requiring hospitalization in Canadians prior to, during, and 30 days following discharge. To analyze effects of patient/disease characteristics, treatment, and regional differences in costs.</AbstractText>
<AbstractText Label="METHODS">Study utilized previously recorded clinical characteristics, resource use, and outcomes of laboratory-confirmed influenza patients admitted to hospitals in the Serious Outcomes Surveillance (SOS), Canadian Immunization Research Network (CIRN), from 2010/11 to 2012/13. Unit costs including hospital overheads were linked to inpatient/outpatient resource utilization before and after admissions.</AbstractText>
<AbstractText Label="RESULTS">Dataset included 2943 adult admissions to 17 SOS Network hospitals and 24 Toronto Invasive Bacterial Disease Network hospitals. Mean age was 69.5 years. Average hospital stay was 10.8 days (95% CI: 10.3, 11.3), general ward stays were 9.4 days (95% CI: 9.0, 9.8), and ICU stays were 9.8 days (95% CI: 8.6, 11.1) for the 14% of patients admitted to the ICU. Average cost per case was $14 612 CAD (95% CI: $13 852, $15 372) including $133 (95% CI: $116, $150) for medical care prior to admission, $14 031 (95% CI: $13 295, $14 768) during initial hospital stay, $447 (95% CI: $271, $624) post-discharge, including readmission within 30 days.</AbstractText>
<AbstractText Label="CONCLUSION">The cost of laboratory-confirmed influenza was higher than previous estimates, driven mostly by length of stay and analyzing only laboratory-confirmed influenza cases. The true per-patient cost of influenza-related hospitalization has been underestimated, and prevention programs should be evaluated in this context.</AbstractText>
<CopyrightInformation>© 2017 The Authors. Influenza and Other Respiratory Viruses Published by John Wiley & Sons Ltd.</CopyrightInformation>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Ng</LastName>
<ForeName>Carita</ForeName>
<Initials>C</Initials>
<AffiliationInfo><Affiliation>ICON Plc, Vancouver, BC, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ye</LastName>
<ForeName>Lingyun</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Noorduyn</LastName>
<ForeName>Stephen G</ForeName>
<Initials>SG</Initials>
<AffiliationInfo><Affiliation>GSK, Mississauga, ON, Canada.</Affiliation>
</AffiliationInfo>
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<ForeName>Margaret</ForeName>
<Initials>M</Initials>
<AffiliationInfo><Affiliation>ICON Plc, Vancouver, BC, Canada.</Affiliation>
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<Author ValidYN="Y"><LastName>Thommes</LastName>
<ForeName>Edward</ForeName>
<Initials>E</Initials>
<AffiliationInfo><Affiliation>Takeda (formerly GSK), Oakville, ON, Canada.</Affiliation>
</AffiliationInfo>
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<ForeName>Ron</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>McMaster University, Hamilton, ON, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Ambrose</LastName>
<ForeName>Ardith</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Andrew</LastName>
<ForeName>Melissa K</ForeName>
<Initials>MK</Initials>
<AffiliationInfo><Affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Hatchette</LastName>
<ForeName>Todd</ForeName>
<Initials>T</Initials>
<AffiliationInfo><Affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Boivin</LastName>
<ForeName>Guy</ForeName>
<Initials>G</Initials>
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</Author>
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<Initials>M</Initials>
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<Initials>J</Initials>
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</AffiliationInfo>
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<Initials>M</Initials>
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</AffiliationInfo>
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<Initials>D</Initials>
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</AffiliationInfo>
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<ForeName>Anne</ForeName>
<Initials>A</Initials>
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</AffiliationInfo>
</Author>
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<ForeName>Janet</ForeName>
<Initials>J</Initials>
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</AffiliationInfo>
</Author>
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<ForeName>Allison</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Mount Sinai Hospital, Toronto, ON, Canada.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Andre</ForeName>
<Initials>A</Initials>
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</AffiliationInfo>
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<ForeName>Jeff</ForeName>
<Initials>J</Initials>
<AffiliationInfo><Affiliation>Michael Garron Hospital, Toronto, ON, Canada.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>David</ForeName>
<Initials>D</Initials>
<AffiliationInfo><Affiliation>Department of Infectious Diseases and Medical Microbiology, William Osler Health System, Brampton, ON, Canada.</Affiliation>
</AffiliationInfo>
</Author>
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<ForeName>Rohita</ForeName>
<Initials>R</Initials>
<AffiliationInfo><Affiliation>GSK, Mississauga, ON, Canada.</Affiliation>
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<Initials>M</Initials>
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<Initials>S</Initials>
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<Initials>D</Initials>
<AffiliationInfo><Affiliation>The Moncton Hospital, Moncton, NB, Canada.</Affiliation>
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<ForeName>Grant</ForeName>
<Initials>G</Initials>
<AffiliationInfo><Affiliation>University of British Columbia, Vancouver, BC, Canada.</Affiliation>
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<Initials>S</Initials>
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</AffiliationInfo>
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<ForeName>Louis</ForeName>
<Initials>L</Initials>
<AffiliationInfo><Affiliation>Université de Sherbrooke, Sherbrooke, QC, Canada.</Affiliation>
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<ForeName>Duncan</ForeName>
<Initials>D</Initials>
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</Author>
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<ForeName>Shelly A</ForeName>
<Initials>SA</Initials>
<AffiliationInfo><Affiliation>Canadian Center for Vaccinology, IWK Health Centre and Nova Scotia Health Authority, Dalhousie University, Halifax, NS, Canada.</Affiliation>
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</Author>
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<Month>01</Month>
<Day>24</Day>
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<QualifierName UI="Q000191" MajorTopicYN="Y">economics</QualifierName>
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<Keyword MajorTopicYN="Y">burden of illness</Keyword>
<Keyword MajorTopicYN="Y">direct service costs</Keyword>
<Keyword MajorTopicYN="Y">disease surveillance</Keyword>
<Keyword MajorTopicYN="Y">hospital costs</Keyword>
<Keyword MajorTopicYN="Y">human</Keyword>
<Keyword MajorTopicYN="Y">influenza</Keyword>
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<Month>11</Month>
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<ArticleId IdType="doi">10.1111/irv.12521</ArticleId>
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<ReferenceList><Reference><Citation>Vaccine. 2007 Jun 28;25(27):5086-96</Citation>
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</ReferenceList>
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   |texte=   Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.
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	Serveur d'exploration sur la grippe au Canada
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Serveur d'exploration sur la grippe au Canada

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.

Resource utilization and cost of influenza requiring hospitalization in Canadian adults: A study from the serious outcomes surveillance network of the Canadian Immunization Research Network.

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